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Biology, 29.05.2020 08:59 ineedhelp2285

Individuals without AFS have a glutamic acid at position 487 on the ALDH2 protein, whereas individuals with AFS have a lysine at this position. Using what you determined in 1.2, provide a plausible chemical explanation justifying why the properties of the enzyme could be so drastically altered by this single amino acid substitution. Keep in mind that the enzyme has two substrates, one of which is acetaldehyde and the other is NADH or NAD+

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Individuals without AFS have a glutamic acid at position 487 on the ALDH2 protein, whereas individua...
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