A patient has a genetic disorder that has resulted in the absence of functioning white blood cells. Which responses will be lacking when a pathogen enters the patient's bloodstream?

A) Skin forming a physical defense; stomach acid forming a chemical defense

B) Macrophages ingesting pathogens; stomach acid forming a chemical defense

C) Macrophages ingesting pathogens; basophils releasing histamine

D) Skin forming a physical defense; basophils releasing histamine