Energy conservation in thioesters, acetyl-CoA and succinyl-CoA:
O ensure irreversibility of the citrate synthase reaction, in the case of acetyl-CoA.
O ensure the production of GTP in the case of succinyl-CoA.
O in the case of acetyl-CoA is required because OAA concentration in the cell are very low due to the endergonic nature of the malate dehydrogenase reaction.
O occurs through large enzyme complexes.