The fixed pattern of changes in membrane potential during an action potential is coordinated by the sequential opening and closing of voltage-gated ion channels. Can you identify the status (open/closed) of the voltage-gated Na and K channels during each phase of an action potential?

Na-K channels

Explanation:

Brief sequential change in the membrane potential of excitable cells after stimulus is called action potential whereas membrane potential represent charge difference across the membraneIn a typical neuron cell, membrane potential of cytoplasm is negative at rest and hence called resting membrane potential Resting membrane potential of excitable cells is established by Na+ K+ pump and maintained by K+ leaky channels at rest Phases of action potential includes: depolarization, repolarization, hyperpolarization and resting membrane potential Depolarization starts when a threshold stimulus is applied on a neuron when via Na+ mechanically operated channels that trigger action potential Depolarization of membrane potential is due to influx of Na+ via voltage gated Na+ channels Repolarization starts with the efflux of K+ by the opening of voltage gated K+ channels, voltage gated K+ channels starts to open when voltage gated Na+ channels becomes occurs due to excessive efflux of K+ by voltage gated K+ channels Additional efflux of K+ occurs due to slow inactivation of voltage gated K+ channel  

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