ATP is a cosubstrate of the enzyme PFK-1. In most species ATP is also an inhibitor of PFK-1 at higher concentrations. This seems to violate Le Chatelier's Principle. Which statement below would provide a suitable explanation?

A) PFK-1 must be phosphorylated by ATP in the active site and the phosphorylated PFK-1 must be the less active form. B) There must be another cofactor interacting with ATP at high concentrations to achieve inhibition of PFK-1.C) ATP actually activates the reverse of the reaction preceding the PFK-1 step in the pathway. It likely has no direct effect on PFK-1.D) There are two sites on PFK-1 that bind ATP. One is the active site; the other is the regulatory site where inhibition occurs.

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You want to cultivate some exotic plants at your farm. however, the climate is chillier than the temperature range favorable to the crop. which is the best method to use for the cultivation of this exotic crop? a. use a crop rotation method b. use a lot of fertilizer c. prepare the seed bed properly d. use a greenhouse e. use irrigation

Choose the incorrect statement (a) the motor end plate membrane is only capable of generating graded potentials, but it is contiguous with the skeletal muscle sarcolemma, which can generate action potentials. (b) propagation of an action potential through the t-tubules into the sarcoplasmic reticulum triggers the release of ca++ into the cytoplasm of a skeletal muscle fiber. (c) the generation of suprathreshold endplate potentials in multiple muscle fibers could be due to the increased frequency of action potential generation at the axon hillock of a single motor neuron. (d) a greater amount of ach would be found in the presynaptic vesicles of a motor unit that fired several action potentials after exposure to botulinum toxin, than in a motor unit that fired several action potentials after exposure to the venom of the krait snake (which contains α-bungarotoxin).