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Biology, 22.04.2020 04:27 beav0919cnnowyfe2
Sickle cell anemia is caused by a single point mutation, in one of the exons that codes for the synthesis of β-globin. The picture below shows the DdeI restriction sites in the normal and sickle cell alleles of the β-globin gene. Notice that the mutation that causes sickle cell eliminates the second DdeI site. On the gel provide below draw what the restriction fragments would look like for an individual that is homozygous for the normal allele (AA), for an individual that is a heterozygous carrier (AS), and for an individual with sickle cell disease (SS). How many bands would appear on the gel of the heterozygote?
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Sickle cell anemia is caused by a single point mutation, in one of the exons that codes for the synt...
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