The Friends of the Earth recommend seven principles for the effective assessment and oversight of synthetic biology. Which of those principles states, "Synthetic biology requires the strictest levels of physical, biological and geographic containment as well as independent environmental risk assessment for each proposed activity or product"

economic impact of malaria is estimated to cost africa $12 billion every year. this figure factors in costs of health care, absenteeism, days lost in education, decreased productivity due to brain damage from cerebral malaria, and loss of investment and tourism.

before, trains worked using the steam engine. thus, it uses heat so it is crucial to apply heat balance. the steam engine absorbs energy during the stage of boiling water. so, this is the endothermic reaction. when the steam is used to work the piston, it has to release this energy through running the train. the excess energy is released as an exhaust to the chimney. this is the exothermic process because it releases energy to the surroundings.