Which organ system is responsible for regulating body temperature

Simplified it's actually many systems that work together, just in different ways!

Explanation:

A large part of the body that is responsible for the regulation of temperature is the nervous system. The hypothalamus, which is a portion of the brain, controls the regulation of body temperature. The process that allows the human body to maintain its core temperature is called thermoregulation. The hypothalamus sends signals to various parts of the body, such as the glands and nervous system, when its core internal temperature begins to fluctuate too high or low.

However, the endocrine and the excretory systems also play a role in the regulation of body temperature.

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