Enhancers can act over long stretches of DNA, but are specific about which genes they affect.
How do eukaryotic cells prevent these transcription regulators from looping in the wrong direction and inappropriately turning on the transcription of a neighboring gene?

a. The cell uses histone acetyltransferase to prevent enhancer binding to the DNA.
b. The cell will group neighboring genes into operons so that they are transcribed as a single unit, regulated by a single enhancer.
c. Chromosome loop-forming proteins arrange the DNA into topological associated domains such that individual genes and their associated enhancer binding regions are in proximity.
d. There is no mechanism to prevent inappropriate enhancer action on neighboring genes. The cells will degrade inappropriately produced mRNA molecules.