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Biology, 04.04.2020 14:11 ssargeant2559

Geneticists analyze pedigrees to follow the inheritance of genetically controlled conditions. Three things must be determined in a pedigree analysis:

The mode of inheritance of the condition. In this tutorial, this means deciding if a condition is caused by an autosomal dominant or autosomal recessive allele.

The genotypes of individuals in the pedigree (as far as can be known) based on their phenotype and the phenotypes of their parents or children.

The probability that certain individuals will have the condition. This requires assigning probability values to some individuals whose genotypes cannot be determined with certainty. It also requires an understanding of how and when to apply the product and sum rules.

Part A - Determining the mode of inheritance

The pedigrees below show the inheritance of three separate, rare autosomal conditions in different families. For each pedigree, decide if the condition is betterexplained as recessive or dominant.

Drag the correct label to the appropriate location. Labels can be used once, more than once, or not at all.

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