Sickle-shaped red blood cells result from a mutation in the gene that code for hemoglobin.
This mutation results in sickle-cell anemia. A partial sequence of bases from a normal
hemoglobin gene and a sequence that results in sickle-cell anemia are shown below. *
(5 Points)
What type of mutation is depicted in this sequence?
Substitution
Insertion
Deletion
Frameshift

"Substitution" type of mutation is depicted in this sequence.

Option: A

Explanation:

When a nucleotide base is altered, substituted or removed from RNA or a DNA sequence in genetic mutation, is understood as substitution or point mutation. Such mutation affect the downstream protein output in a number of way, and provide outcome that are somewhat foreseeable depending on the mutation details. This occur in the hemoglobin β-globin chain, which allows the hydrophilic amino acid glutamic acid to be substituted by the hydrophobic amino acid valine in 6th location.

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