Gaucher disease type 1 (GD1 ) is a recessive genetic disease that affects 1 in 900 individuals in a particular population. GD1 is caused by a mutation in the enzyme glucocerebrosidase. Assuming the population is in Hardy-Weinberg equilibrium, calculate the frequency of the wild-type (nonmutant) allele for the enzyme glucocerebrosidase.

Using the Hardy-Weinberg equilibrium equation, the frequency for the wild-type allele (referred to as p, see explanation below) comes out to be

Explanation:

An individual will have to be homozygous recessive for the mutation in the enzyme glucocerebrosidase to have the Gaucher disease type 1 (GD1). This percentage will be

= × 100 =

= =

We know that because the sum of both allele frequencies has to be 100%

So

Hence,

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white blood cells or wbc s are mainly 2 types-

1.agranulocytes

2.granulocytes

the monocytes or macrophages of agranulocytes , dendritic cells which are accessory leucocytes, and b cells which is one type of lymphocytes   identify the antigens present on the pathogen's surface. these three cells are called antigen presenting cells(apc) which are phagocytes and destroy the antigens by secreting antitoxins. besides this leukocyte is always plays vital role in the immunity of the body.