Oct4
Oct4
Pluripotency
Differentiation
A model of pluripotent vs differentiated cellular gene expression is shown. Pluipotency is found in stem cells that
have the ability to become multiple types of cells. Differentiation is the process where a cell becomes specialized
and cannot return to its pluripotent state. What explanation best supports the model of pluripotency and
differentiation shown above?
Differentiated cells have different DNA sequences that
pluripotent cells and can produce different protein products.
Differentiated cells have fewer gene sequences that pluripotent
cells and can only produce limited numbers of proteins.
Pluripotent cells recruit molecules from nearby cells to increase
gene expression while differentiated cells use only internal
transcription factors.
Differentiated cells and pluripotent cells have different types of
activator or repressor proteins present that positively and
negatively regulate gene expression in the cell.
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