Why are nonsense substitution likely to be more damaging than missense substitutions?

What best explains the inability for life to exist in earth early atmosphere

The hematodinium parasite becomes less of a problem for the blue crab when the crab is very young. fishing is thriving in the region. the crab moves to less salty water. a significant percentage of the population is impacted.

Natural resources are any materials that humans obtain from the earth to meet our wants and needs.