Which of the following pairs is mismatched? RNA polymerase – makes a molecule of RNA from an RNA template DNA ligase – joins segments of DNA DNA gyrase – relaxes supercoiling in DNA ahead of the replication fork transposase – cuts DNA backbone, leaving "sticky ends" DNA polymerase – makes a molecule of DNA from a DNA template

RNA polymerase – makes a molecule of RNA from an RNA template

Explanation: RNA polymerase is an enzyme that catalyzes the copying of a DNA sequence into an RNA sequence during transcription. RNA polymerase uses a DNA template for the synthesis of an RNA strand. RNA polymerase is also called DNA-dependent RNA polymerase. During transcription, DNA helicase unwinds the double helix of the DNA while the RNA polymerase catalyzes the synthesis of an RNA strand from the DNA.