Form a hypothesis about the effect of a mistake in seperating homologous chromosmes during meiosis

The phlogiston theory in the 17th century attempted to explain burning. the theory stated that combustable objects contained a material called phlogiston, a substance without mass, color, odor, etc. after objects burned, the objects were dephlogistonated and were then in their true form. the phlogiston theory was accepted until the 18th century, when lavoisier proved that combustion requires a gas that has mass. phlogiston is considered a) to be scientific knowledge b) not to be scientific knowledge c) to be proven by scientific method d) to be accepted in the modern scientific community

This question is only for applicants to scholars for medicine or scholars for dental medicine: what aspects about medicine (or dental medicine) intrigue you? describe how these aspects influence your life. (100-650 words)

The kidney filters potentially toxic substances in the blood, and thus “clears” the blood of those substances. this clearance function is dependent upon and proportional to the diffusion gradient of the substance across filtering capillaries, i.e. if the concentration of the substance is doubled, twice as much will be cleared from each ml of blood that is filtered. suppose that the body produces a constant amount of a substance x per unit of time. the kidneys eliminate substance x at a rate directly proportional to the concentration of the substance and the volume of blood cleared each minute (c): elimination = c × [x], where [x] is the steady-state concentration of substance x. imagine an individual with an initial concentration of x equal to [x]0 who develops kidney disease. her baseline clearance c0 drops to one half of the original (½c0). what is the new steady state concentration of x? (for simplicity, assume that substance x is 100% filtered by the kidney).