A cell has been subjected to X-ray irradiation, causing a significant number of mutations in the genome. Which of the following would you NOT expect to occur as a result?
(A) Activation of the protein kinase ATR
(B) Activation of the protein kinase Chk1
(C) Inactivation of the protein phosphatase Cdc25
(D) Binding of p53 to Mdm2
(E) Stabilization of p53
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