In genetic diseases like Down syndrome, the cause is often due to the presence of an extra chromosome. Do you think this mutation would occur in meiosis or mitosis? Why?

The mutation observed in the down syndrome occurred as a result of a abnormal and non disjuncted meiosis.

Explanation:

Howbeit, mutation can be described as any heritable change of the base-pair sequence of genetic material.

Down syndrome also described as trisomy 21 is a medical condition caused by a chromosomal excess, whereby the patients bear a certain resemblance to the Mongoloid race, such as a small head and tilted eyelids, and typically have a delay in cognitive ability and physical growth.

Meiosis is one that describes the cell division process of a diploid cell into four haploid cells, which develop to produce gametes.

The chromosomal mutation of nondisjunction in down syndrome describes how a pair of chromosomes is not fully separated during meiosis, resulting in the gamete having an extra chromosame (or none at all).

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