In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with cell surface proteoglycans, then with specific receptors. This is later followed by viral capsids docking with nuclear pores. Afterward, the capsids go from being full to being "empty." Which of the following best fits these observations? A) The viral envelope mediates entry into the cell, the capsid mediates entry into the nuclear membrane, and the genome is all that enters the nucleus. B) Only the genetic material of the virus is involved in the cell's infectivity, and is injected like the genome of a phage. C) The viral capsid mediates entry into the cell, and only the genomic DNA enters the nucleus, where it may or may not replicate. D) The viral envelope is not required for infectivity, since the envelope does not enter the nucleus.
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In electron micrographs of HSV infection, it can be seen that the intact virus initially reacts with...
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