Insulin is a protein that is produced by pancreatic cells and secreted into the bloodstream. Which of the following options correctly lists the order of the structures through which insulin passes from its production to its exit from the cell?

The question can be answered on the basis of general transport of proteins.

The endomembrane system is present in the eukaryotes that includes the cell organelle that divides them into the structural and functional unit of the cell. This helps in the protein sorting and its transport.

The insulin is the hormone that made of the alpha and beta peptide through the disulfide linkage. The protein must enter in the rough endo plasmic reticulum for the signal recognition and modification of protein. Then the protein moves into the golgi through the vesicles and finally into the endocytosis through the cell membrane.