Genetic disorders can result when sister chromatids fail to separate properly.
During which phase is this problem most likely to occur?

Anaphase Il of meiosis is the phase in which sister chromatids fail to separate properly from each other. It is a genetic disorder.

This nondisjunction also occurs in mitosis of cell division. It cannot pass from parents to offspring because mitosis occurs in body cells not sex cells. This nondisjunction in mitosis causes serious disease such as cancer. Cancer disease also contain abnormal number of chromosome.