Which of the following mRNA sequences could code for the polypeptide met-arg-ser-leu-glu?
5' ATGGAGGTTCGATGCGTA 3'
5' AUGAGUAGCUUCGAGUGG 3'
5' AUGCGUAGCUUGGAGUGA 3'
5' AUGCUAAAUGUGCGAUGA 3'

5'-AUGCGUAGCUUGGAGUGA-3'  

Explanation:

(a) Break the string into triplets.

5'-AUG-CGU-AGC-UUG-GAG-UGA-3'

The string contains six codons.

The initiation codon is AUG (Met)

That eliminates Options 1 and 4.

(b) Identify the stop codon

There are six codons, so the sixth is the stop codon, which must be UAA, UGA, or UAG .

That eliminates Option 2, which ends with UGG.

The correct answer must be Option 3.

(c) Check

Translate the codon string.

5'-AUG-CGU-AGC-UUG-GAG-UGA-3

    met   arg    ser    leu    glu    stop

That's the correct sequence.

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