Integrins are transmembrane proteins that can reversibly link the cytoskeleton of a cell to the extracellular matrix. When there is a transient period during which the cytoskeleton is not linked to the extracellular matrix, the result may be.

Integrins are trans-membrane proteins that can reversibly link the cytoskeleton of a cell to the extracellular matrix. When there is a transient period during which the cytoskeleton is not linked to the extracellular matrix, the result may be movement of cell through the extracellular matrix.

Explanation:

The adherence of cell to the extracellular matrix is important to maintain the formatuon of tissue and cell-cell communication.Several factors contribute to adhere the cells to the matrix .Among them ,Integrins are one.Integrins are transmembrane proteins that establish a link between the extracellular matrix and the actin filaments of the cytoskeleton.The integrins play a major role as receptors during signal transduction.The activity of the integrins to attatch the cells to the matrix is regulated within the cell.When the integrins are regulated to lose their adhesive activity the cells become free to move through the extracellular matrix.

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