How do the sequence and composition of amino acids in a protein influence how a protein folds up

See the explanation below, please.

Explanation:

The amino acid sequence of a protein will determine the interactions inside and with the environment (that is, it will influence the conformations that are adopted at physiological temperature: the degrees of freedom). Example: the proline amino acid (Pro) has a cyclic structure, which implies a limitation in the random movement of the polypeptide chain.

In proteins, the primary structure determines the sequence of the amino acid sequence of the polypeptide chain (amount of amino acids present and their order by means of peptide bonds).