Which statement regarding chronic myeloid leukemia (CML) is a true statement?1. It is not seen in children.2. It represents 30% of all cases of leukemia.3. The average age of onset is older than 70 years.4. Affected persons carry the Philadelphia chromosome.

Answer is 4. Affected persons carry the Philadelphia chromosome.

Explanation:

The Philadelphia chromosome got its name from the city where it was discovered in 1960 by Nowell and Hungerford.

The Philadelphia chromosome is known to be an abnormal chromosome, which is found sometimes in the leukocyte. It is known to be responsible for causing chronic myeloid leukemia,CML.

The chronic myeloid disorder is the cancerof the white blood cell, i.e the leukocytes.

It  occurs in this leukemia. CML occurs occasionally in children and adolescents.  represents approximately 15% of all cases of leukemia in the US. The average age of onset is between 40-50 years.

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