Horses and donkeys can mate, but they produce a mule, which is always a sterile animal. this means that they cannot produce viable offspring and are isolated.

I am not sure if this is a true or false question, but if it is, the answer would be true. Donkeys are the offspring of a jack (or a male donkey) and a mare (or a female horse). Most mules are sterile, due to their chromosomes. When they do not have homologous pairs, it results in interspecies hybrids, like the mule. Hope this helps.

Dis the correct answer thats what i put and it was right