Infections arising from the periapical region of the mandibular first premolars perforate through the lingual cortex to thea- pterygomaxillary spaceb- submental spacec- sublingual spaced- submandibular space

The correct answer is option C- "Sublingual space".

Explanation:

If an infection perforate from he mandibular first premolars through the lingual cortex, it is very likely that it continues is way into the sublingual space. The infections located at the sublingual space are often bacterial infections that comes precisely from the floor of the mouth. If an infection goes into the lingual cortex, it will often go to the tissue under the tongue at the sublingual space.