How might an amino acid change at a site distant from the active site of the enzyme alter the enzyme's substrate specificity?

a. by changing the enzyme's stability

b. by changing the enzyme's location in the cell

c. by changing the shape of the protein

d. by changing the enzyme's ph optimum

e. an amino acid change away from the active site cannot alter the enzyme's substrate specificity

Answer is C. By changing the shape of protein.

Explanation:

The site where the substrate binds and the chemical reaction take place is known as the active site.

Note that , if there is changes in the pH, it can affect the active site of the amino acid residue which usually have acidic or basic properties that is important for catalysis, thereby making it hard for substrate to bind.

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