What happens if p53 is mutated?

Most TP53 mutations change single amino acids in the p53 protein, which leads to the production of an altered version of the protein that cannot control cell proliferation and is unable to trigger apoptosis in cells with mutated or damaged DNA. As a result, DNA damage can accumulate in cells

both male and female gametes are produced by meiosis of the germ cells. therefore, both male and female gametes are haploid. one male and one female gamete unite during the fertilization to form the diploid zygote. in seed bearing plants, pollen grain is the male gametophyte, which produces sperm cells.