Many proteins destined for the mitochondria are not folded properly prior to their destination. this ultimately means that the proteins will be inactive in the cytosol, while active in the mitochondrial matrix. what function do these proteins most likely serve? why is it advantageous to have them be active in the mitochondrial matrix and not in the cytosol?

Mitochondrial proteins are generally involved in mitochondrial functioning and the functions they carry out

Explanation:

Mitochondrial proteins are synthesized in the cortisol by the ribosomes and are delivered as precursors to the mitochondria before folding and remodeling processes takes place which are carried out by the chaperones.

Mitochondrial proteins which resides in the matrix and the cristae are involved generally in mitochondria functions such as carrying the reactions in the electron transport chain among others.

The proteins which are already active at the cortisol may remain there, which is why it is advantageous for the proteins to be in their precursor state so that they will be properly targeted to the matrix to be synthesized and to function.

the oldest known insects are believed to live around 400 millions ago as suggested by the fossil records.   some plants having woody stems also evolved during this time.

after the evolution of insects the first four legged species or the tetrapods evolved in shallow freshwater habitats from the intermediate species approximately 397 million years ago. the tetrapods went on conquering the land giving rise to amphibians, reptiles, mammals and birds.

the major split in tetrapods first occurred 340 million years ago branching off from amphibians.

363 million years ago when the carboniferous period began the insects started roaming on land and taking flights, following which the four limbed tetrapods adapted in the terrestrial habitat.