subject
Biology, 10.11.2019 03:31 Valfrutos2912

Enalapril is an anti-hypertension "prodrug" (i. e., a drug precursor) that is inactive until the ethyl ester (arrow in figure) is hydrolyzed by esterases present in blood plasma. the active drug is the dicarboxylic acid ("enalaprilat") that results from this hydrolysis reaction. part aenalaprilat is a competitive inhibitor of the angiotensin-converting enzyme (ace), which cleaves the blood-pressure regulating peptide angiotensin i. ace has a km = 52 μm for angiotensin i, which is present in plasma at a concentration of 75 μm. when enalaprilat is present at 2.4 nm, the activity of ace in plasma is 10% of its uninhibited activity. what is the value of ki for enalaprilat? express your answer to two significant figures and in units of m.

ansver
Answers: 2

Another question on Biology

question
Biology, 22.06.2019 00:30
Consider this plant cell which organelle is labeled g
Answers: 1
question
Biology, 22.06.2019 05:30
How is transcription similar to translation in terms of base pairing?
Answers: 3
question
Biology, 22.06.2019 09:20
Amap's orientation is typically determined by an
Answers: 2
question
Biology, 22.06.2019 11:20
Drag each label to the correct location on the chart. match the function to the type of tissue
Answers: 2
You know the right answer?
Enalapril is an anti-hypertension "prodrug" (i. e., a drug precursor) that is inactive until the eth...
Questions
question
Mathematics, 03.12.2021 01:00
question
Mathematics, 03.12.2021 01:00
Questions on the website: 13722363