•the other new strand in the fork must be synthesized in the opposite direction, requiring dna polymerase to
synthesize the new strand in short 5' to 3' segments with periodic starts and stops. this strand is called the
strand; replication of this strand is done in segments called
- named
after the japanese scientist who discovered them.
after both new strands are made, the enzyme dna polymerase then converts the short
_sequences, laid
down by the primase, into
finally, the enzyme
is the "glue that mends all the okazaki fragments resulting in the two double
belix molecules that are identical to each other and to the original molecule.

Bisphenol a (often called bpa) is a chemical found in products that people use every day, from water bottles to food containers to children's toys. unfortunately, bpa leaches out of its many products and makes its way into our bodies. what are the health effects of bpa exposure? ongoing research is finding that elevated exposure to bpa can affect a wide variety of developmental and physiological processes, but one of the first studies of bpa's health effects came about because of a simple mistake in the lab. at a laboratory at case western reserve university in 1998, geneticist patricia hunt was making a routine check of her female lab mice. as she extracted and examined developing eggs from the ovaries, she began to wonder what had gone wrong. she noticed that many of the eggs showed problems with their chromosomes, and some had irregular amounts of genetic material, which can lead to miscarriages and birth defects in mammals. she learned that a lab assistant had mistakenly washed the plastic mouse cages and water bottles with a harsh soap, releasing bpa from the plastic. knowing that bpa is an endocrine disruptor, a chemical that can enter organisms and mimic hormones, hunt set out to discover whether it had adversely affected her mice.