Stimulation of the neurons in the "pleasure pathway" (the site in the brain that seems to be involved in the experience of pleasure) is probably most responsible for causing the "high" associated with cocaine use.

The correct answer is dopamine.

Explanation:

The pleasure pathway also termed as a reward pathway. It is a dopaminergic or dopamine stimulated pathway in the brain. These are groups of projection neurons present in the brain.  These projections secrete the neurotransmitter called dopamine. It is related to happiness or reward hormones stimulate during pleasure.

Cocaine exhibits addictive effects by acting on, a set of interconnected parts that manage pleasure by producing dopamine.

Thus, the correct answer is dopamine.