Would the pi values of the animal insulins be the same as, greater than, or less than human insulin?

The pI values for animals and human insulin are the same, with the exception of duck and chicken insulin.

The pI value is the isoelectric point of the protein or amino acid chain. The isoelectric point can be given as the pH value at which the net charge of the insulin molecule is zero.

The insulin molecule is composed of amino acids that are charged at a specific pH. With the change in the pH, charge transfer takes place and results in the net-zero pH at pI.

The changeable amino acids in animal insulin and human insulin are the same. Thus, the pI values for human and animal insulin are the same.

The exceptions to the condition are duck and chicken insulin.

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They would be similar basically the same

Explanation:

This is because, amino acid changes all involved neutral amino acids. Chicken insulin would be more basic whereas duck would be more acidic.

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