List the genetic disorders found on chromosome 11. what do you know about any of those disorders?

The following diseases and disorders are some of those related to genes on chromosome 11:

autism (neurexin 1), acute intermittent porphyria, albinism, ataxia–telangiectasia, Beckwith–Wiedemann syndrome, Best's disease, beta-ketothiolase deficiency, beta thalassemia, bladder cancer, breast cancer, carnitine palmitoyltransferase I deficiency, Charcot–Marie–Tooth disease, Cystic fibrosis, Depression,

Denys–Drash syndrome, familial Mediterranean fever, Hereditary angioedema OMIM: 106100, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Mantle cell lymphoma (t11;14), Meckel syndrome,

methemoglobinemia, beta-globin type, Mixed lineage leukemia, multiple endocrine neoplasia type 1,

Hereditary multiple exostoses, Niemann–Pick disease, nonsyndromic deafness, porphyria,

Potocki–Shaffer syndrome,

Romano–Ward syndrome, Sickle cell anemia, Smith–Lemli–Opitz syndrome, tetrahydrobiopterin deficiency, Usher syndrome, WAGR syndrome, Wiedemann–Steiner syndrome, Wilms' tumor.

Explanation:

Jacobsen syndrome is a rare chromosomal disorder resulting from deletion of genes from chromosome 11. The severity of symptoms depends on the number of deletions; but they include serious intellectual disabilities, dysmorphic features, delayed development and a variety of physical problems including heart defects.

Chromosome 11  contains the 135 million base pairs of the nucleotide and constitute around 4.5% of total DNA. More than 50 coding genes are present on this chromosome.

The different genetic disorders associated with chromosome 11 disorder are   autism (neurexin 1), Beckwith–Wiedemann syndrome, Charcot–Marie–Tooth disease and Potocki–Shaffer syndrome. Jacobsen syndrome may be defined as thedisorder occurs due gene deletion from chromosome 11. The symptoms depends on the number of deletions of the genes on chromosome 11 and include  delayed development, dysmorphic features and a variety of physical problems including heart defects.

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