The chart above shows the allele frequencies for a normal hemoglobin (a allele) and a sickle cell hemoglobin (s allele).
which can correctly be inferred from the chart when looking at the allele frequency changes that have occurred over the
three generations?

B

Explanation:

There is a correlation between malaria infested regions and the allele frequency of sickle cell anemia, because the non sickle cell allele frequency is decreasing faster than the sickle cell allele frequency. The S allele is being selected for during natural selection in these areas. The S allele frequency is changing far less than the A allele frequency. This shows that the A allele is being selected against, therefore, there are far fewer of those alleles being inherited in each generation compared to the S allele. This selection of the S allele coincides with the correlation that exists in malaria infested areas and sickle cell anemia.

the correct answer is 2 and 4