The immune response requires a team effort. how do the specific and non-specific defenses work together? explain your answer.

A non-specific immune response (also called immunity) is antigen-independent while a specific immune response is antigen-dependent. The examples of the non-specific immunity are fever, phagocytosis by macrophages, skin and mucus.  The example of the specific immune response is cytotoxic T-cells able to recognize antigens on infected cells and kill them before the infection could spread.

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme