Why are insertion and deletion mutations so harmful?

the insertion on removal of mutations are dangerous in nature.  the process is basically just one large gamble to see what it does. and even though we have a decent understanding of the genomes of many animals and plants, we still dont know everything. so if we tamper with certain genes we may cause a evolution or we might kill the subject and the potential for it to procreate.

explanation:

the universal gravitation equation. since the gravitational force is directly proportional to the mass of both interacting objects, more massive objects will attract each other with a greater gravitational force. if the mass of one of the objects is doubled, then the force of gravity between them is doubled.

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