Why or how are calories "wasted" during gluconeogenesis?

luconeogenesis is a ubiquitous process, present in plants, animals, fungi, bacteria, and other microorganisms.[2] In vertebrates, gluconeogenesis takes place mainly in the liver and, to a lesser extent, in the cortex of the kidneys. In ruminants, this tends to be a continuous process.[3] In many other animals, the process occurs during periods of fasting, starvation, low-carbohydrate diets, or intense exercise. The process is highly endergonic until it is coupled to the hydrolysis of ATP or GTP, effectively making the process exergonic. For example, the pathway leading from pyruvate to glucose-6-phosphate requires 4 molecules of ATP and 2 molecules of GTP to proceed spontaneously. Gluconeogenesis is often associated with ketosis. Gluconeogenesis is also a target of therapy for type 2 diabetes, such as the antidiabetic drug, metformin, which inhibits glucose formation and stimulates glucose uptake by cells.[4] In ruminants, because dietary carbohydrates tend to be metabolized by rumen organisms, gluconeogenesis occurs regardless of fasting, low-carbohydrate diets, exercise, etc.[5]

humans can cause extinction of a species through overharvesting, pollution, habitat destruction, introduction of invasive species (such as new predators and food competitors), overhunting, and other influences. explosive, unsustainable human population growth is an essential cause of the extinction crisis.

explanation:

i didn't have the answer choices , but i tried my best.

when a reversible reaction is occurring in both directions at the same rate; the products and reactants do not change in concentration. a chemical reaction where the compound is broken into its constituent parts.