How is an impulse sent through a neuron?

When a nerve impulse reaches the end of an axon, the axon releases chemicals called neurotransmitters. Neurotransmitters travel across the synapse between the axon and the dendrite of the next neuron. Neurotransmitters bind to the membrane of the dendrite

Iwould say overuse ( but not 100% sure ) in the u.s. we tend to overuse water by leaving it running, throwing it away, taking long showers, etc.