Atherosclerotic peripheral vascular disease is symptomatic with at least 50% occlusion. the primary peripheral symptom, due to ischemia, is:

Atherosclerotic peripheral vascular disease is symptomatic with at least 50% occlusion. The primary peripheral symptom, due to ischemia, is calf pain.
This disease is a form of arterial insufficiency, which means that blood circulation through the arteries is decreased.Other symptoms include painful cramping in the hip, thigh or calf muscles after certain activities, such as walking or climbing stairs (claudication) and leg numbness or weakness.

Answer; 
Calf pain; 
Atherosclerotic peripheral vascular disease is symptomatic with at least 50% occlusion. the primary peripheral symptom, due to ischemia, is calf pain.

Explanation;
Atherosclerosis can affect the arteries in the heart, legs, brain, kidneys and other organs. Peripheral vascular disease, peripheral arterial disease and lower extremity vascular disease occurs in the vessels that carry blood to the arms and the legs. 
Ischemia is a restriction in blood supply to tissues, which results to a shortage of oxygen needed for respiration. 

Ithink it’s c or b for the answer.