In controlled longitudinal studies, the u. s. women's health initiative found that taking estrogen and progesterone the risk of heart disease, stroke, and breast cancer.

In controlled longitudinal studies, the U.S. women's Health Initiative found that taking estrogen and progesterone increased the risk of heart disease, stroke, and breast cancer.
Women take progesterone by mouth for inducing menstrual periods; and treating abnormal uterine bleeding associated with hormonal imbalance, and severe symptoms of premenstrual syndrome. The use of estrogen and progesterone causes various effects on the body of women, these includes heart disease, stroke, and breast cancer.