The origin of congenital adrenal hyperplasia occurs when circulating cortisol levels

The origin of congenital adrenal hyperplasia occurs when circulating cortisol levels are low.
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease which results from mutations of genes for enzymes involved in the biochemical steps of production of mineralocorticoids, glucocorticoids or sex steroids from cholesterol by the adrenal glands (steroidogenesis). Low cortisol production results in rising levels of ACTH (adrenocorticotropic hormone) because cortisol usually inhibits ACTH production. This increased ACTH production induces overgrowth (hyperplasia) and overactivity of the steroid-producing cells of the adrenal cortex.

Vijina kid

Proteins are the workhorses of the cell, controlling virtually every reaction within as well as providing structure and serving as signals to other cells. proteins are long chains of  amino acids  , and the exact sequence of the amino acids determines the final structure and function of the protein. instructions for that sequence are encoded in  genes  . to make a particular protein, a messenger ribonucleic acid (mrna) copy is made from the gene (in the process called  transcription  ), and the mrna is transported to the  ribosome  . protein synthesis, also called  translation  , begins when the two ribosomal subunits link onto the mrna. this step, called initiation, is followed by elongation, in which successive amino acids are added to the growing chain, brought in by transfer rnas (trnas). in this step, the ribosome reads the  nucleotides  of mrna three by three, in units called  codons  , and matches each to three nucleotides on the trna, called the anticodon. finally, during termination, the ribosome unbinds from the mrna, and the  amino acid  chain goes on to be processed and folded to make the final, functional protein